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. 2011 Jul 18;32(8):991–998. doi: 10.1038/aps.2011.81

Figure 4.

Figure 4

Effects of RGZ on Bcl2 and Bax as well as Caspase3 expression in AGEs-treated SH-SY5Y cells. SH-SY5Y cells were treated with 1000 μg/mL AGEs for 24 h, with or without incubation of 10 μmol/L RGZ and 10 μmol/L GW9662. (A) The mRNA of Bcl2. (B) The mRNA of Bax. (C) The mRNA of activated Caspase3. (D) The protein expression of Bcl2. (E) The protein expression of Bax. (F) The protein expression of activated Caspase3. Data are shown as mean±SD (n=3 independent experiments). bP<0.05, cP<0.01 compared with the control group. eP<0.05, fP<0.01 compared with AGEs-treated group. hP<0.05, iP<0.01 compared with AGEs+RGZ-treated group.