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. 2013 Nov 18;34(12):1560–1567. doi: 10.1038/aps.2013.163

Table 1. The correlation between PIK3CA hypomethylation and demographic features of esophageal cancer patients.

  n Average methylation rate (%) P-value
Total number 32 6.00±2.80
Age≤45 years >45 years 8 24 5.77±2.51 6.74±3.63 t=−0.845, P=0.405
Male Female 23 9 5.79±2.63 6.56±3.30 t=−0.689, P=0.496
Tumor size≤3 cm 3–5 cm ≥5 cm 5 23 4 6.94±4.53 5.85±2.23 5.77±3.93 F=0.318, P=0.730
Positive lymph nodes Negative lymph nodes 14 18 5.49±2.76 6.41±2.84 t=−0.917, P=0.366
TNM stage I TNM stage II TNM stage IIIa+IIIb, IV 6 16 10 8.52±2.55 6.42±2.36 3.84±2.08* PI–III=0.001 PII–III=0.01

Comparisons of single samples were performed with the Student's t-test and ANOVA test.

*, Stage III and IV specimens were analyzed in one category.