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. Author manuscript; available in PMC: 2015 Apr 2.
Published in final edited form as: Oncogene. 2013 Oct 28;33(40):4867–4876. doi: 10.1038/onc.2013.439

Figure 1.

Figure 1

A. Cell counts of SCLC cells treated with vehicle (black lines) or with ganetespib at IC50 concentration (red lines), at the indicated time points. Solid lines represent total number of cells, whereas dotted lines represent viable cells, as counted by Trypan blue staining. The data were derived from three independent experiments. Bars indicate standard errors. B. & C. G2/M phase arrest of GLC4 and H82 cells 24-hrs after ganetespib treatment at the indicated concentrations. D. Cells were treated with ganetespib for 72 hrs followed by drug washout for another 72 hrs. Note that ganetespib-induced G2/M arrest is still present 72 hours after ganetespib washout in H82, GLC4 and H146 cells.