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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: FEMS Microbiol Rev. 2013 Dec 19;38(3):493–522. doi: 10.1111/1574-6976.12050

Figure 1. Events controlled by regulated proteolysis during bacterial development.

Figure 1

(A) Destruction of a regulatory protein by a protease, e.g., a Clp protease that processively degrades a regulatory protein.

(B) Activation of a regulatory protein by a protease, e.g., a protease (often dedicated to one specific substrate) that non-processively cleaves an inactive proprotein to produce the active regulatory protein.

(C) Production of an intercellular signal by a protease. In many cases, the protease(s) remains to be identified. A precursor protein is cleaved one or more times to produce a protein, peptide, or amino acid that acts as an intercellular signal.