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Histological analysis of pulmonary sections from immunized mice with or without As2O3 treatment. (a) Unsensitized mice show healthy pulmonary tissue. (b) Mice sensitized and challenged with OVA show cells infiltrating the airways. After As2O3 treatment (2.5 mg/kg (c) and 5 mg/kg (d)), cellular infiltration was reduced. (a–d) Sections are stained with H&E. Original magnification in a–d, ×100; upper left figures: ×400. As2O3, arsenic trioxide; H&E, hematoxylin–eosin; OVA, ovalbumin.
