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Effects of repeated ip injections of dexmedetomidine (DEX) on increase in Iba-1 (a microglial marker) expression in the spinal dorsal horn induced by monoarthritis (MA). (A) Immunohistochemistry for Iba-1 in the ipsilateral spinal transverse sections on day 5 after sham MA, MA, and MA with multiple DEX-treatment. (B) Quantification of Iba-1 expression on both sides of the spinal dorsal horn. cP<0.01 (n=4).
