Table 6. Comparison of pharmacokinetics between male and female patients administered pegylated liposomal doxorubicin.

Parameters	Male (n=6)	Female (n=3)	P Valuea
AUC(0–∞) (g/L·h)	0.8±0.5	1.1±0.3	0.316
AUC(0–t) (g/L·h)	0.6±0.3	0.9±0.2	0.234
CL (L·h−1·m−2)	0.051±0.027	0.027±0.008	0.199
Cmax (mg/L)	9.5±2.9	10.8±3.6	0.605
t1/2 (h)	61±31	83±16	0.298
tmax (h)	4±4	12.±11	0.331
Vd (L/m2)	3.7±1.2	3.3±1.1	0.684

^aParameters of male vs female.