Table 2. The genotype frequencies of FGFR gene in NSCLC and controls.
NSCLC | Control | Adjusted | 95% CI | Adjusted | |||||
---|---|---|---|---|---|---|---|---|---|
n | % | n | % | OR | P valuea,b | ||||
rs351855G/A | GG | 193 | 30.68 | 163 | 22.36 | Ref | |||
GA | 331 | 52.62 | 391 | 53.64 | 0.715 | 0.554 | 0.922 | 0.030 | |
AA | 105 | 16.69 | 175 | 24.01 | 0.507 | 0.368 | 0.697 | 0.000 | |
G | 717 | 57.00 | 717 | 49.18 | Ref | ||||
A | 541 | 43.00 | 741 | 50.82 | 0.730 | 0.627 | 0.850 | 0.000 | |
rs145302848C/G | CC | 163 | 25.91 | 179 | 24.55 | Ref | |||
CG | 320 | 50.87 | 365 | 50.07 | 0.963 | 0.742 | 1.249 | 0.775 | |
GG | 146 | 23.21 | 185 | 25.38 | 0.867 | 0.640 | 1.174 | 0.435 | |
C | 646 | 51.35 | 723 | 49.59 | Ref | ||||
G | 612 | 48.65 | 735 | 50.41 | 0.932 | 0.801 | 1.084 | 0.360 | |
rs147603016G/A | GG | 167 | 26.55 | 189 | 25.93 | Ref | |||
GA | 304 | 48.33 | 366 | 50.21 | 0.940 | 0.726 | 1.216 | 0.638 | |
AA | 158 | 25.12 | 174 | 23.87 | 1.028 | 0.762 | 1.387 | 0.508 | |
G | 638 | 50.72 | 744 | 51.03 | Ref | ||||
A | 620 | 49.28 | 714 | 48.97 | 1.013 | 0.871 | 1.178 | 0.871 |
aBinary logistic regression was applied. Data was adjusted with gender, age, tumor histology, disease stage, and chemotherapy regimen.
bCorrected with Bonferoni correction.