Figure 1.
PE-induced proliferation in VSMCs. Quiescent (growth arrested) VSMCs were stimulated in the absence (control) or presence of PE (10 μmol/L), prazosin (10 μmol/L), timolol (1 mg/mL), CsA (0.5 μg/mL) and chelerythrine (20 μmol/L), or various combinations of these for 48 h. Optical density and cell numbers were measured. n=5 experiments. Mean±SD. cP<0.01 vs control; eP<0.05 vs PE; hP<0.05 vs chelerythrine+PE group or CsA+PE group.