Skip to main content
. 2009 Apr 13;30(5):617–627. doi: 10.1038/aps.2009.33

Figure 1.

Figure 1

Schematic DNA structures of Ad-ETK and Ad-TK. Ad-ETK: the structure of TERTp-regulated conditionally replicative adenovirus, Adv-TERTp-E1A-IRES-TK. The endogenous E1A promoter was replaced with the TERT promoter to control the expression of E1A and TK genes. ITR: inverted terminal repeat. Ad-TK: the structure of TERTp-regulated replication incompetent adenovirus. Adv-TERTp-GFP-IRES-TK: the endogenous E1A promoter was replaced with the TERT promoter to control the expression of GFP and TK genes.