Figure 3.

Dose-response data for the antitussive effect induced by CA-Ver in mice. The antitussive effects were assessed 60 min after the administration of each drug. Each point or column represents the mean±SEM for ten mice in each group. ^bP<0.05, ^cP<0.01 vs the value for the respective vehicle-treated group (open column). The dose of codeine phosphate was 30 mg/kg. CA-Ver and codeine phosphate were suspended in a 0.5% carboxyl methylcellulose solution. Vehicle: 0.5% carboxyl methylcellulose solution.