Table 2.
Clinical data and tryptase values of patients with NSAID hypersensitivity as well as the hymenoptera venom allergy group
| NSAID | Comparison group: hymenoptera venom allergy | P values | |
|---|---|---|---|
| Number of patients |
284 |
484 |
n.a. |
| Mean age (range) |
51 (10–89) |
47 (7–81) |
.026 |
| Male/female |
81/203 |
287/197 |
< .001 |
| Severity of anaphylaxis |
|
|
< .001 |
| Grade 1 |
174 (61.3%) |
26 (5.4%) |
|
| Grade 2 |
110 (38.7%) |
249 (51.4%) |
|
| Grade 3 |
0 (0.0%) |
209 (43.2%) |
|
| Application |
|
|
n.a. |
| Oral |
249 |
n.a. |
|
| Intravenous |
14 |
n.a. |
|
| Intramuscular |
19 |
n.a. |
|
| Suppository |
2 |
n.a. |
|
| Basal serum tryptase |
|
|
.004 |
| Minimum [ng/mL] |
0.0 |
0.0 |
|
| Maximum [ng/mL] |
94.8 |
148.0 |
|
| Mean [ng/mL] |
5.9 |
7.8 |
|
| 0.0 to 5.0 ng/mL |
166 (58.5%) |
276 (57.0%) |
|
| > 5.0 to 10.0 ng/mL |
92 (32.4%) |
125 (25.8%) |
|
| > 10.0 ng/mL |
26 (9.2%) |
83 (17.1%) |
|
| > 10.0 to 20.0 ng/mL |
20 (7.0%) |
54 (11.2%) |
|
| > 20.0 to 50.0 ng/mL |
5 (1.8%) |
24 (5.0%) |
|
| > 50.0 ng/mL | 1 (0.4%) | 5 (1.0%) |
P values calculated from the comparison between patients with NSAID hypersensitivity and hymenoptera venom allergy. n.a., not applicable.