Figure 1.

Simvastatin 50 mgkg⁻¹·d⁻¹ for 3 weeks impacts atherosclerosis in ApoE^−/− mice. Shown are representative aortic sinus sections stained with Oil Red O (A–C; Scale bar=50 μm). (D) Mean atherosclerotic lesion area in the aortic sinus was determined. n=5–6 mice per condition. ApoE^−/−/S: ApoE^−/− mice treated with simvastatin. ^bP<0.05, ^cP<0.01 vs wild-type. ^fP<0.01 vs ApoE^−/−.