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. 2014 Apr 23;14:282. doi: 10.1186/1471-2407-14-282

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Copyright © 2014 Chen et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Effects of HBSP on tumorigenicity of B[alpha]P-treated Huh-7 hepatoma cells in nude mice. BALB/c nude mice were inoculated with either the Huh-7/HBSP/B[alpha]P or Huh-7/GFP/B[alpha]P. Tumor size was measured every 3 days. All mice were sacrificed after 21 days of inoculation. (A) The resulting tumors photographed on the 21st day after inoculation. (B) The tumors dissected out from the sacrificed mice. (C) BPED-DNA in tumor tissues detected by immunohistochemistry assay. Images were taken at × 400 magnification. (D) Weights of tumors dissected out from the sacrificed mice (* P < 0.01). (E) Tumor volume during growth, results were expressed as mean ± SD.