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. 2011 Jun 13;9(1):34–44. doi: 10.1038/cmi.2011.16

Figure 3.

Figure 3

Phenotypic and functional comparisons of Vδ1 and Vδ2 subsets. PBMCs from four healthy donors were cultured in the presence of immobilized anti-γδ TCR antibody for 2 weeks, then either the Vδ1 or Vδ2 subset was obtained via magnetic cell sorting, and the expression of CD6, NKG2D, CD27 and CD45RA (a), the expression of CD107a, PD1 and production of TNF-α and IFN-γ without and with PMA/Ion restimulation (b), and the cytotoxic effects against Daudi and K562 cells (c) of both subsets were compared. *P<0.05. IFN, interferon; Ion, ionomycin; PBMC, peripheral blood mononuclear cell; PD1, programmed-death receptor 1; PMA, phorbol 12-myristate-13-acetate; TCR, T-cell receptor; TNF, tumour-necrosis factor.