Table 1. Baseline characteristics of PBC patients.
Group (n) | Sex (F/M) | Age (years) | ALT (U/l) | AST (U/l) | ALP (U/l) | γ-GGT (U/l) | TBil (umol/l) | AMA (+/−) | ANA (+/−) |
---|---|---|---|---|---|---|---|---|---|
Advanced (12) | 11/1 | 51.0±9.5 | 115.5±114.2 | 130.5±110.9 | 479.8±325.7 | 669.5±424.9 | 66.6±72.4 | 10/2 | 9/3 |
Remission (9) | 7/2 | 62.1±13.2 | 41.0±24.8 | 63.3±41.8 | 146.9±49.7* | 110.4±86.5* | 29.8±29.7 | 8/1 | 6/3 |
*P<0.01 versus patients with advanced stage PBC; values are mean±standard deviation. PBC patients were divided into two groups: advanced stage (ALP>2UNL, and γ-GGT>3UNL) and remission stage (ALP≤2UNL, and γ-GGT≤3UNL) of the disease.
Abbreviations: ALP, alkali phosphatase; ALT, alanine aminotransferase; AMA, antimitochondrial antibody; ANA, antinuclear antibody; AST, aspartate aminotransferase; PBC, primary biliary cirrhosis; TBil, total bilirubin; UNL, upper normal limit; γ-GGT, γ-glutamyltranspeptidase.