Table 2. Clinical data of 10 PBC patients who underwent liver biopsy.
| Group (n) | Early stage (6) | Advanced stage (4) |
|---|---|---|
| Sex (F/M) | 5/1 | 4/0 |
| Age (years) | 44.3±6.5 | 43.2±6.6 |
| ALT (U/l) | 103.0±63.0 | 239.5±93.7* |
| AST (U/l) | 104.6±53.4 | 192.9±126.2 |
| ALP (U/l) | 304.9±239.0 | 533.4±306.5 |
| γ-GGT (U/l) | 252.6±286.8 | 687.3±427.6 |
| TBil (umol/l) | 25.0±13.7 | 72.4±56.8 |
| DBil (umol/l) | 11.5±8.7 | 50.1±47.2 |
| IgM (g/l) | 5.7±3.1 | 3.9±1.3 |
| AMA (+/−) | 6/0 | 1/3 |
| ANA (+/−) | 4/2 | 3/1 |
*P<0.05 versus early stage of the disease (Scheuer's classification stages I and II); values are mean±standard deviation.
Abbreviations: ALP, alkali phosphatase; ALT, alanine aminotransferase; AMA, antimitochondrial antibody; ANA, antinuclear antibody; AST, aspartate aminotransferase; DBil, direct bilirubin; IgM, immunoglobulin M; PBC, primary biliary cirrhosis; TBil, total bilirubin; γ-GGT, γ-glutamyltranspeptidase.