Table 2. Cytokine-producing T cells and T-cell subsets in patients and healthy controls.

Parameter	Patient (no. 57)	Control (no. 20)
IL-4 (% CD3+CD4+)	1.97 (0.54–5.2)	5.69 (1.99–14.22)
IFN-γ (% CD3+CD4+)	2.18 (0.53–8.02)	5.73 (3.78–12.09)
IL-2 (% CD3+CD4+)	2.01 (0.17–6.2)	12.16 (4.44–17.82)
TNF-α (% CD3+CD4+)	2.48 (0.92–13.21)	15.75 (7.25–27.41)
CD3+CD4+ (% lymphocytes)	55.57 (21.89–77.78)	38.6 (18.9–45.6)
CD3+CD8+ (% lymphocytes)	16.61 (7.95–51.3)	29.95 (11.4–35.2)
CD4+CD25+Foxp3+ (% lymphocytes)	9.52 (4.13–17.02)	3.65 (1.52–7.14)

Data show the median (range); P values for all patients were statistically different from controls (P<0.0001).

Abbreviations: IFN, interferon; TNF, tumor-necrosis factor.