Table 3. Number of visible tumors in the liver surface of mice treated with different dosages of tanshinone II-A.
| Group | Dose (mg·kg−1·d−1) | Mice (before/after) | Number of liver metastases | P-value |
|---|---|---|---|---|
| C0 | 0 | 10/10 | 18±5 | |
| C1 | 5 | 10/10 | 15±4 | P>0.05 |
| C2 | 20 | 10/10 | 10±4 | P<0.05 |
| C3 | 80 | 10/10 | 5±3 | P<0.01 |
Dose refers to mg-kg−1·d−1 of tanshinone IIA for five weeks and before/after means no treatment of five weeks after tanshinone II-A treatment at the indicated dose. The liver tissues were observed visually, and the number of visible tumors on the liver surface were counted.