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Mean plasma concentration-time profiles of omeprazole after id administration of omeprazole (3 mg/kg) to rabbits in the presence of ketoconazole (60 mg/kg, administered intraduodenally) or verapamil (9 mg/kg, administered intraduodenally) respectively. Each point indicates the Mean±SD (n=6). (♦)Control (alone); (▪) Coadministered with ketoconazol; (▴) Coadministered with verapamil.
