Table 1. Biochemical parameters of serum after 16-week treatment with baicalin (80 mg·kg−1·d−1 ip) in rats fed a HFD. bP<0.05 vs STD+Veh; eP<0.05 vs HFD+Veh.
| STD+Veh | HFD+Veh | HFD+Baicalin | |
|---|---|---|---|
| Total cholesterol (mg/dL) | 66.0±4.5 | 118.5±16.5b | 67.6±5.2e |
| LDL cholesterol (mg/dL) | 10.8±0.9 | 16.7±1.7b | 8.35±2.41e |
| Triglyceride (mg/dL) | 109.7±8.7 | 90.2±6.3 | 89.4±7.3 |
| NEFA (mmol/L) | 1.13±0.12 | 3.32±0.52b | 0.66±0.17e |
| Glucose (mg/dL) | 111.1±5.3 | 174.2±5.4b | 145.6±12.7e |
| Insulin (ng/mL) | 0.842±0.071 | 1.443±0.169b | 0.796±0.131e |
| TNFα (pg/mL) | 320.1±13.7 | 808.5±109.8b | 479.8±23.3e |
Values are means±SEM. STD+Veh, rats fed a standard diet and received an intraperitoneal administration of vehicle; HFD+Veh, rats fed a high-fat diet and received an intraperitoneal administration of vehicle; HFD+ baicalin, rats fed a high-fat diet received an intraperitoneal admini stration of 80 mg/kg baicalin once a day; NEFA, nonesterified fatty acids. Means in a row with different superscripts differ significantly.