Table 2. Comparison of pharmacokinetic parameters between mice in AAI group and that in BNF+AAI group. n=5. Values are expressed as mean±SD. bP<0.05, cP<0.01 vs AAI group.
Groups | Cmax (μg/mL) | tmax (min) | AUC (min·μg/mL) | t1/2 (min) |
---|---|---|---|---|
AAI | 8.73±1.57 | 16.00±5.48 | 418.37±126.09 | 27.55±3.37 |
AAI+BNF | 3.08 ±0.61c | 6.25±2.50b | 149.84±20.30b | 31.46±8.80 |