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. 2013 Jul 15;34(8):1025–1035. doi: 10.1038/aps.2013.75

Figure 3.

Figure 3

TLR2 blockade stabilizes advanced atherosclerotic plaques. In the TLR2ab-treated and TLR2-deficient groups, Sirius red staining revealed increased collagen content (A). Immunohistochemical staining revealed more abundant smooth muscle cell distribution (B) and decreased macrophage accumulation (C) in lesions in the brachiocephalic artery. The scale bars represent 50 μm. L indicates the lumen. The data are shown as the means±SEM (n=10 mice/group). bP<0.05, cP<0.01 vs the saline-treated group.