Table 1. Cytotoxicity profile of compounds 90 and 91 against tumor and non-tumor cell lines, IC50 (μmol/L)a.
| Cell line | Phidianidine A (90) | Phidianidine B (91) |
|---|---|---|
| C6 | 0.642±0.2 | 0.98±0.3 |
| HeLa | 1.52±0.3 | 0.417±0.4 |
| CaCo-2 | 35.5±4 | 100.2±8.5 |
| 3T3-L1 | 0.14±0.2 | 0.786±0.3 |
| H9c2 | 2.26±0.6 | 5.42±0.8 |
a IC50 values are expressed as mean±SEM (n=24) of the three independent experiments. Bold values show IC50 of less than 1 μmol/L.