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Emodin suppressed 11β-HSD1 activity in the mesenteric fat of ob/obmice. Ob/ob mice were subjected to intraperitoneal injection treatment twice daily with vehicle (0.5% Tween 80), 25 mg/kg emodin or 50 mg/kg emodin for 26 d. 11β-HSD1 activity in the mesenteric fat was measured by SPA at the end of the treatment period. Values are expressed as fold of the values for the vehicle group. bP<0.05 vsvehicle group; n=6.
