Figure 5.

Effects of emodin on serum lipids of ob/ob mice. ob/ob mice were subjected to intraperitoneal injection twice daily with vehicle (0.5% Tween 80), 25 mg/kg emodin or 50 mg/kg emodin for 26 d. A pair-fed group was set by providing the ob/obmice each day with the amount of food eaten by freely fed 50-mg/kg emodin-treated mice. Serum triacylglycerol (A), cholesterols (B) and NEFA (C) concentrations were evaluated at the end of the treatment period. Data are expressed as the mean±SEM. ^bP<0.05, ^cP<0.01 vs vehicle group; n=8.