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. 2011 Feb 14;8(2):146–149. doi: 10.1038/cmi.2010.63

Table 3. Overall performance of the three-assay algorithma.

  Parameters calculated according to manufacturer cutoffs Parameters calculated according to ROC CutOffs
Group Sensitivity Specificity PPV NPV Sensitivity Specificity PPV NPV
Children 0.98 0.80 0.74 0.98 0.98 0.93 0.89 0.99
Adults 0.90 0.81 0.81 0.89 0.90 0.93 0.90 0.90
Children+adults 0.94 0.80 0.77 0.95 0.94 0.92 0.89 0.96

Abbreviations: PPV, positive predictive value; NPV, negative predictive value.

a

The statistical parameters were calculated with the MedCalc statistical software. Borderline results were regarded as positive results.