Table 2. Biological effects of celiac disease autoantibodies.
Effect describe | References | ||
---|---|---|---|
In vitro | |||
Induction of epithelial proliferation | 69 and 70 | ||
Inhibition of epithelial differentiation | 69 | ||
Increase in epithelial permeability | 71–73 | ||
Interference with gliadin up-take | 74 | ||
Inhibition of angiogenesis | 75 and 76 | ||
Increase in vascular permeability | 77 | ||
Induction of neuronal apoptosis | 78 | ||
Binding to placental tissue | 79 | ||
Induction of trophoblast apoptosis | 80 | ||
In vivo | |||
Induction of ataxia | 81 | ||
No effect | 82–84 |