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. 2014 May;143(5):633–644. doi: 10.1085/jgp.201311112

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© 2014 Gao et al.

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Figure 4. — Photochemical transformation of the HCN channel is oxygen dependent. Solutions used in the experiments were degassed and then purged with pure N₂ or O₂. (A and B) Current traces before (black; no. 3 in C and D) and after laser pulses (blue; no. 8 in C and D). *, the group of O₂ is significantly different from the data groups of Normal air + trolox and N₂ (one-way ANOVA). (C and D) τ_deactivation or percentage of I_inst versus episode number. 0.5 µM FITC-cAMP was applied to the bath solution. *, the groups of O2 and normal air are significantly different from the other two data groups.