Figure 17.
LCR propagation is inhibited by high NCX density. Both panels show LCR events in a steady-state depolarization to −34 mV, the voltage at which NCX would be in equilibrium with 100 nM of cytosolic calcium. In the top panel, kNCX is 150 mM/ms, whereas in the bottom panel, it is 17.5 (full red, 500 nM saturation; black, 100 nM minimum).