Table 1.
Nanomaterial delivery amounts and dosage quantifications
| Nanomaterial and concentration, μg/μL | Particles per embryo, ng | Particles per human, ng | Dosage, μg/m2 | Dosage, mg/kg |
|---|---|---|---|---|
| Cop-IO | ||||
| 2.5E−08 | 3.6E−08 | 0.26 | 1.5E−04 | 4.4E−09 |
| 0.25 | 0.36 | 2.6E+06 | 1.5E+03 | 0.04 |
| 0.71 | 1.0 | 7.6E+06 | 4.3E+03 | 0.13 |
| 1.1 | 1.5 | 1.1E+07 | 6.5E+03 | 0.19 |
| 1.9 | 2.8 | 2.0E+07 | 1.2E+04 | 0.34 |
| Thermo-IO | ||||
| 4.5E−08 | 6.5E−08 | 0.48 | 2.7E−04 | 7.9E−09 |
| 0.45 | 0.65 | 4.8E+06 | 2.7E+03 | 0.08 |
| 1.3 | 1.8 | 1.4E+07 | 7.8E+03 | 0.23 |
| 1.9 | 2.8 | 2.0E+07 | 1.2E+04 | 0.34 |
| 3.5 | 5.0 | 3.7E+07 | 2.1E+04 | 0.61 |
| Ag | ||||
| 3.0E−08 | 4.30E−08 | 0.32 | 1.8E−04 | 5.3E−09 |
| 3.0E−04 | 4.30E−04 | 3.2E+03 | 1.8 | 5.3E−05 |
| 0.03 | 0.04 | 3.2E+05 | 1.8E+02 | 5.3E−03 |
| 3.0 | 4.3 | 3.2E+07 | 1.8E+04 | 0.53 |
| Au | ||||
| 7.0E−07 | 1.0E−06 | 7.5 | 4.3E−03 | 1.2E−07 |
| 7.0E−04 | 1.0E−03 | 7.5E+03 | 4.3 | 1.2E−04 |
| 0.07 | 0.10 | 7.5E+05 | 4.3E+02 | 0.01 |
| 7.0 | 10 | 7.5E+07 | 4.3E+04 | 1.2 |
| TiO2 | ||||
| 7.0E−07 | 1.0E−06 | 7.5 | 4.3E−03 | 1.2E−07 |
| 0.07 | 0.10 | 7.5E+05 | 4.3E+02 | 0.01 |
| 3.5 | 5.1 | 3.7E+07 | 2.1E+04 | 0.62 |
| 7.0 | 10.0 | 7.5E+07 | 4.3E+04 | 1.2 |
| SWCNTs/MWCNTs | ||||
| 5.0E−10 | 7.2E−10 | 5.3E−03 | 3.1E−06 | 8.9E−11 |
| 5.0E−04 | 7.2E−04 | 5.3E+03 | 3.1 | 8.9E−05 |
| 0.05 | 0.07 | 5.3E+05 | 3.1E+02 | 8.9E−03 |
| 5.0 | 7.2 | 5.3E+07 | 3.1E+04 | 0.89 |
Abbreviations: IO, iron oxide; SWCNT, single-wall carbon nanotube; MWCNT, multiwall carbon nanotube; Ag, silver; Au, gold; TiO2, titanium dioxide; Cop, coprecipitation; Thermo, thermal decomposition.