Table 3.
Comparison of socio-demographic factors and glucose control of hypertensive patients with and without diabetes who were statins users or non-users
|
Hypertensive patients with DM (n = 507) |
Hypertensive patients without DM (n = 553) |
|||||
|---|---|---|---|---|---|---|
|
Statin users |
Statin non users |
P value (95% CI) |
Statin users |
Statin non users |
P value (95% CI) | |
| n = 415 | n = 92 | n = 396 | n = 157 | |||
| Age (years) Mean (SD) |
61.71 (9.29) |
62.17 (12.02) |
0.728* (-2.176, 3.107) |
62.80 (10.30) |
60.52 (12.23) |
0.039* (-4.463, -0.111) |
| Gender n (%) |
|
|
|
|
|
|
| Men |
176 (84.6) |
32 (15.4) |
0.178** |
155 (70.8) |
64 (29.2) |
0.725** |
| Women |
239 (79.9) |
60 (20.1) |
|
241 (72.2) |
93 (27.8) |
|
| Ethnicity n (%) |
|
|
|
|
|
|
| Malay |
137 (83.5) |
27 (16.5) |
0.737** |
116 (73.0) |
43 (27.0) |
0.808** |
| Chinese |
160 (80.4) |
39 (19.6) |
|
220 (71.0) |
90 (29.0) |
|
| Indian |
115 (81.6) |
26 (18.4) |
|
54 (70.1) |
23 (29.9) |
|
| Others |
3 (100.0) |
0 (0.0) |
|
6 (85.7) |
1 (14.3) |
|
| Duration of diabetes (years) |
n = 406 |
n = 84 |
|
|
|
|
| Mean (SD) |
8.169 (6.556) |
7.020 (6.255) |
0.141* |
|
|
|
| HbA1c# |
n = 372 |
n = 77 |
|
n = 72 |
n = 33 |
|
| Mean IFCC unit (SD) mmol/mol |
62 (19) |
57 (17) |
0.030* (-9.610, -0.494) |
44 (5) |
42 (6) |
0.082* (-3.972, 0.242) |
| Mean NGSP unit (SD)% |
7.8 (1.7) |
7.3 (1.6) |
0.034* (-0.871, -0.034) |
6.1 (0.4) |
6.0 (0.5) |
0.089* (-0.363, 0.026) |
| FBG# |
n = 397 |
n = 87 |
|
n = 350 |
n = 131 |
|
| Mean (SD) mmol/L |
7.71 (2.98) |
7.25 (2.55) |
0.179* (-1.142, 0.213) |
5.39 (0.53) |
5.27 (0.58) |
0.029* (-0.231, -0.012) |
| TG# |
n = 383 |
n = 84 |
|
n = 361 |
n = 137 |
|
| Mean (SD) mmol/L |
1.602 (0.737) |
1.965 (1.289) |
0.014* (0.075, 0.653) |
1.416 (0.623) |
1.357 (0.628) |
0.346* (-0.182, 0.064) |
| HDL# |
n = 383 |
n = 84 |
|
n = 361 |
n = 137 |
|
| Mean (SD) mmol/L |
1.269 (0.317) |
1.204 (0.322) |
0.092* (-0.140, 0.011) |
1.465 (0.420) |
1.373 (0.380) |
0.026* (-0.173,-0.011) |
| Body Mass Index |
n = 232 |
n = 44 |
|
n = 150 |
n = 58 |
|
| Mean (SD) Kg/m2 |
28.02 (5.37) |
27.74 (4.70) |
0.744* (-1.990, 1.423) |
27.44 (4.67) |
26.73 (5.35) |
0.350* (-2.189, 0.778) |
| Diabetic medication n (%) |
|
|
|
|
|
|
| Yes |
391 (83.7) |
76 (16.3) |
<0.001** |
|
|
|
| No |
24 (60.0) |
16 (40.0) |
|
|
|
|
| On diuretic and/or beta-blocker n (%) |
|
|
|
|
|
|
| Yes |
201 (80.1) |
50 (19.9) |
0.305** |
196 (74.5) |
67 (25.5) |
0.148** |
| No | 214 (83.6) | 42 (16.4) | 200 (69.0) | 90 (31.0) | ||
DM = Diabetes mellitus; HbA1c = Glycated haemoglobin; FBG = Fasting blood glucose; TG = Triglyceride; HDL = HDL-Cholesterol.
IFCC = International Federation of Clinical Chemistry; NGSP = National Glycohemoglobin Standardization Program.
# Most recent result in the past one year.
*Independent sample t-test.
**Chi-square test.