FIG. 3.

Infection of DC by MHV-A59 is mediated by the virus receptor, murine CEACAM1a. The JAWS II DC line and primary cultures of BALB/c and p/p BMDC were incubated with anti-CEACAM1a MAb CC1 that blocks binding of virus to the receptor, an isotype-matched control MAb, or with no antibody (No Ab) and inoculated with MHV-A59. Infected cells were detected 8 h after inoculation by immunofluorescence with antibody to the viral nucleocapsid protein.