Table 2. Effects of atRA on body weight and blood chemistry.
| Group | Initial |
Final (14 week) |
||||
|---|---|---|---|---|---|---|
| Body weight (g) | Body weight (g) | ALT (U/L) | GLU (mmol/L) | TG (mmol/L) | CHO (mmol/L) | |
| Sham+vehicle (n=7) | 283±12 | 546±14 | 80.7±10.6 | 8.53±0.63 | 0.83±0.15 | 1.91±0.14 |
| 5/6Nx+vehicle (n=8) | 289±16 | 538±23 | 75.0±13.9 | 7.46±0.94 | 1.29±0.41 | 1.87±0.09 |
| 5/6Nx+atRA1 (n=9) | 284±11 | 529±20 | 74.8±6.9 | 8.08±0.51 | 1.13±0.11 | 1.84±0.10 |
| 5/6Nx+atRA2 (n=10) | 269±8 | 539±13 | 68.4±9.0 | 7.82±0.56 | 1.75±0.29 | 1.88±0.08 |
Values are mean±SEM. n, number of rats. ALT, alanine aminotransferase; GLU, glucose; TG, triglyceride; CHO, cholesterol. There was no statistical difference in body weight or the blood chemical profile in any group.