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. 2010 Oct 18;31(11):1421–1430. doi: 10.1038/aps.2010.101

Figure 4.

Figure 4

Effect of SFN treatment on the changes in oxidative stress in the injured cortex as assessed by ELISA 24 h after TBI in rats. Bar graphs of protein carbonyls (A), 4-HNE (B), and 8-OHdG (C) protein concentrations in sham control, vehicle and SFN-treated injured rats in ipsilateral cortices 24 h after TBI. CCI significantly elevated protein carbonyls, 4-HNE, and 8-OHdG protein concentrations and SFN treatment significantly reduced the injury-induced increases compared with vehicle-treated injured rats. Data are expressed as means±SEM. n=8 rats per group. cP<0.01 vs sham operation group. fP<0.01 vs vehicle group, analyzed by one-way ANOVA.