Table 2. Comparison of cytokines in the duck, chicken, zebra finch, human and mouse genomes.
| Number of genes |
||||||
|---|---|---|---|---|---|---|
| Class | Family | Duck | Chicken | Zebra finch | Human | Mouse |
| Class I cytokines | IL-2 receptor | 7 | 7 | 7 | 8 | 8 |
| IL-3 receptor | 2 | 2 | 1 | 3 | 3 | |
| IL-6 receptor | 8 | 7 | 8 | 12 | 12 | |
| Single-chain family | 4 | 3 | 6 | 6 | 4 | |
| Class II cytokines | Type I interferons | 4 | 6 | 4 | 20 | 17 |
| Type II interferons | 1 | 1 | 1 | 1 | 1 | |
| IL-10 family | 4 | 4 | 4 | 6 | 5 | |
| PDGF family | Cysteine-knot growth factors | 8 | 8 | 8 | 9 | 9 |
| 4-helix bundle growth factors | 0 | 0 | 0 | 2 | 2 | |
| β-trefoil growth factors | 19 | 19 | 21 | 22 | 21 | |
| Other growth factors | 15 | 17 | 18 | 20 | 20 | |
| TNF family | 11 | 11 | 10 | 18 | 18 | |
| IL-1 family | 2 | 3 | 2 | 10 | 9 | |
| IL-17 family | 5 | 5 | 6 | 6 | 6 | |
| TGF-β family | BMP2 subfamily | 2 | 2 | 2 | 2 | 2 |
| BMP5 subfamily | 4 | 4 | 2 | 5 | 5 | |
| GDF5 subfamily | 3 | 2 | 2 | 3 | 3 | |
| VGL subfamily | 1 | 1 | 1 | 2 | 2 | |
| BMP3 subfamily | 2 | 2 | 3 | 2 | 2 | |
| ADMP | 2 | 2 | 2 | 0 | 0 | |
| Intermediate members | 5 | 4 | 5 | 5 | 5 | |
| Activin subfamily | 4 | 2 | 2 | 4 | 4 | |
| TGF subfamily | 3 | 3 | 2 | 3 | 3 | |
| Distant members | 6 | 6 | 6 | 8 | 8 | |
| Chemokines | CC chemokines | 13 | 14 | 12 | 28 | 27 |
| CXC chemokines | 8 | 8 | 8 | 17 | 14 | |
| CXC3C chemokines | 2 | 1 | 2 | 1 | 1 | |
| C chemokines | 1 | 1 | 1 | 2 | 1 | |
| Total | 150 | 149 | 150 | 230 | 218 | |