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. 2004 May;78(10):5423–5437. doi: 10.1128/JVI.78.10.5423-5437.2004

TABLE 2.

Summary of mutant phenotypes

Group no. Location(s) of CA changes Relative infectivity in monkey cells compared to wt Relative ability to compete for restricting factors in monkey cells compared to wt Effect of CspA on infectivity in HeLa cells
1 CypA-binding loop and Ser149 (phosphorylation site) Increase Decrease Increase or no change
2 Helix 3/6 ridge Increase Increase Decrease