Table 3.

Difference in ventilator variables before and after PEEP titration in 20 patients receiving PEEP >10 cm H₂O in the first 24 hours of mechanical ventilation

Variables	Mean change and 95% CI	P value
Δ PEEP, cmH2O	6 (4 to 8)	<0.001
Δ peak airway pressure, cmH2O	16 (10 to 21)	<0.001
Δ plateau pressure, cmH2O	16 (9 to 24)	<0.001
Δ respiratory system compliance, mL/kg/PBW/cmH2O	−0.28 (−0.43 to −0.13)	0.001
Δ Vt, mL/kg PBW	−0.4 (−0.9 to 0.23)	0.211
Δ SaO2, %	−1.7 (−8 to 4)	0.571

PEEP, positive end expiratory pressure Vt, tidal volume; PBW, predicted body weight SaO₂, arterial oxygen saturation