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. 2004 May;78(10):5170–5183. doi: 10.1128/JVI.78.10.5170-5183.2004

FIG.4.

FIG.4.

Phylogenetic tree analyses of IRES and E2/HVR1 sequences from patients A and B. The trees representing the IRES nucleotide sequences were constructed by using the neighbor-joining algorithm and the Kimura two-parameter method in MEGA version 2.1. Trees representing the E2/HVR1 amino acid sequences were constructed by using the neighbor-joining algorithm and p-distances in MEGA version 2.1. Bootstrap values were derived from 500 resamplings of the original data. There was evidence of phenetic compartmentalization of the extrahepatic sequences where indicated (**, P < 0.001; *, P < 0.01 [Mantel test]). B, brain (•); N, lymph node (○); L, liver (▴); S, serum (□).