FIG. 6.

Translation efficiencies of HCV IRES variants from patients A and B in HuH7 and CHME3 cell lines. Translation efficiencies are shown relative to the master serum variant. The results shown represent the means obtained from at least three experiments for each IRES ± standard errors. Differences were tested with analysis of variance and a Bonferroni correction. The following P values refer to comparisons with the master serum sequence: *, P < 0.001; †, P < 0.025; ‡, P = 0.05. There were statistical differences in translation efficiency in HuH7 and CHME3 cells for IRES variants B20 and B5 in patient A (**, P = 0.005).