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. 2014 Apr 10;2014:845763. doi: 10.1155/2014/845763

Table 3.

Effects of mTOR siRNA and cisplatin alone or combined on growth of human ESCC xenograft in nude mice (n = 5).

Group Animal weight Tumor volume at beginning1 Tumor volume at termination Inhibition rate of tumor (%)
Control 20.54 ± 1.23 57.03 ± 10.45 999.28 ± 167.30
siRNA 20.52 ± 2.08 43.62 ± 10.85 416.97 ± 38.12* 58.27
cis 20.38 ± 1.42 39.09 ± 2.08 367.91 ± 61.21* 63.18
siRNA + cis 20.66 ± 1.79 46.28 ± 25.56 232.86 ± 54.23* 76.70

1Tumor volume is expressed as mm3. *P < 0.05, compared to control group.