TABLE 1.
Plaque sizes of mutant viruses at different temperatures
| Virus | Avg plaque size (mm)a:
|
|||
|---|---|---|---|---|
| Without trypsin (33°C) | With trypsin at temp (°C)
|
|||
| 33 | 37 | 39.5 | ||
| WT | 2.0 | 2.5 | 4.0 | 3.8 |
| NA3A2 | 1.3 | 1.9 | 3.0 | 3.0 |
| NA2A5 | 2.0 | 2.5 | 4.0 | 3.8 |
| NA3A7 | 1.5 | 2.3 | 3.4 | 3.4 |
| NA4A10 | 1.9 | 2.4 | 3.8 | 3.6 |
| NA5A14 | 0.8 | 1.2 | 2.5 | 2.5 |
| NA4A19 | 0.8 | 1.2 | 2.0 | 2.0 |
| NA4A23 | 0.7 | 1.5 | 2.0 | 2.0 |
| NA5A27 | PPc | 0.9 | 1.0 (D) | (D)b |
| NA5A31 | PP | 0.7 | 1.0 (D) | (D)b |
| NA(1T2N)NA | PP | 0.9 | 1.4 | 1.2 |
| NATRNA | PP | 0.8 | 1.0 (D) | (D)b |
a
Plaque morphology and size (average of 10 plaques) were determined at 60 h p.i.
b
Diffuse (D) plaques were visible but not measurable.
c
PP, plaques were clear but pinpoint in size.