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An overview of the pathogenesis of oral mucositis. RT: radiotherapy, ROS: reactive oxygen species, CT: chemotherapy, NF-κB: nuclear factor-kappa B, IL: interleukin, TNF-α: tumor necrosis factor-alpha, COX-2: cyclooxygenase-2, and MMP: matrix metalloproteinase. Courtesy of Professor ST Sonis and the Multinational Association of Supportive Care in Cancer (MASCC).
