Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Apr 15;4:4690. doi: 10.1038/srep04690

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014, Macmillan Publishers Limited. All rights reserved

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. The images in this article are included in the article's Creative Commons license, unless indicated otherwise in the image credit; if the image is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the image. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

PMC Copyright notice

(a) The sample configuration, including the tissue, the tube, the excitation and emission fiber bundles, and the HIFU transducer. (b) The schematic diagram of the USF imaging system. PDG: pulse delay generator; FG: function generator; RF-Amp: radio-frequency power amplifier; MNW: matching network; HIFU: high intensity focused ultrasound; Amplifier 1: low noise current preamplifier; PMT: photomultiplier tube; F1: excitation filter; F2–F5: emission filters; Amplifier 2: an amplifier circuit consisting mainly of a high-precision operational amplifier OPA2277. (c) The timing diagram showing the gating pulse to the HIFU transducer and the shutter. The gating pulse to the HIFU determined the heating period (300 ms in this study). During the heating period, the temperature in the focal volume increased continuously. At the final 2 ms of this duration, the shutter was opened to excite the fluorescence signal. At the same time, the oscilloscope was triggered for data acquisition.