Table 3.
Selection pressure for codons with unusual mutations and natural polymorphisms
| Codon | Triplet | PV (%) | dN-dS | dN-dS (N) | P value* | Mutations |
|---|---|---|---|---|---|---|
| 5 |
CTT |
1.67 |
2.29 |
0.48 |
0.285 |
L5F |
| 6 |
TGG |
8.20 |
−5.97 |
−1.26 |
0.996 |
W6R |
| 7 |
CAA |
1.89 |
−15.57 |
−3.29 |
1.000 |
Q7E |
| 29 |
GAT |
2.65 |
20.20 |
4.26 |
0.003 |
D29V |
| 63 |
CCC |
84.77 |
2.01 |
0.42 |
0.196 |
L63A/R/S/V/G/H |
| 70 |
AAA |
9.11 |
−1.51 |
−0.32 |
0.964 |
K70I |
| 79 |
CCT |
2.48 |
4.44 |
0.94 |
0.190 |
P79L |
| 91 |
ACT |
3.33 |
5.01 |
1.12 |
0.086 |
T91V |
| 92 |
CAG |
4.05 |
−15.62 |
−3.46 |
0.990 |
Q92G;Q92K |
| 93 | ATT | 47.97 | 28.64 | 6.34 | 1.000 | I93F |
*P < 0.05 was considered statistically significant for positive pressure.
PV, phenotypic variation; dN, number of non-synonymous substitutions per site (n/N); dS, number of synonymous substitutions per site (s/S); N, normalized; P, probability.