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. 2014 Mar 16;12:69. doi: 10.1186/1479-5876-12-69

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Copyright © 2014 Ye et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Comparison of IL-37 mRNAs and protein levels between SLE and HC. (A) Expressions of IL-37 mRNAs in PBMCs from SLE patients (n = 66) and healthy controls (HC, n = 41) were determined by RT-PCR. Results are depicted as box plots, with median (horizontal line within each box) and 10^th, 25^th, 75^th, and 90^th percentiles (bottom bar, bottom of box, top of box, and top bar, respectively). (B) Serum IL-37 protein levels in SLE patients (n = 66) and healthy controls (HC, n = 41) were determined by ELISA. Each symbol represents an individual SLE patients and healthy controls. Horizontal lines indicate median values. Mann-Whitney U-test and associated P values are indicated.