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. Author manuscript; available in PMC: 2014 Apr 29.
Published in final edited form as: J Trauma. 2009 Sep;67(3):476–484. doi: 10.1097/TA.0b013e3181ad66bb

TABLE 2.

Unadjusted Univariate Comparison of Comorbidities and Preinjury Medications Across Statin and Nonstatin Users

No PIS Use
(n = 224)
(%)
PIS Use
(n = 71)
(%)
P
Comorbidities
  Hypercholesterolemia or
  hyperlipidemia
1.1 23.9 <0.001*
  Hypertension 32.6 74.6 <0.001*
  CHF 2.7 9.9 0.010*
  Previous MI 8.0 22.5 <0.001*
  Previous CABG or stenting 0.7 14.1 <0.001*
  Diabetes 14.3 36.6 <0.001*
  COPD 6.7 14.1 0.051
  Chronic renal disease or
  insufficiency
1.8 4.2 0.239
  Alcoholism 10.7 4.2 0.098
  Liver disease 2.2 2.8 0.778
  Smoking 19.6 21.1 0.785
Preinjury medications
  ACE inhibitors 5.4 21.1 <0.001
  Angiotensin receptor blocker 0.4 5.6 0.003
  ASA 10.7 39.4 <0.001
  β-Blockers 10.3 47.9 <0.001
  Diuretics 3.1 9.9 0.020
  Plavix 3.6 14.1 <0.001
  Coumadin 5.8 12.7 0.055
  Corticosteroids 1.3 4.2 0.133
  NSAIDS 4.9 7.0 0.490
  Calcium channel blockers 2.2 2.8 0.779
  Other direct vasodilators 0.9 2.8 0.222

CHF, congestive heart failure; MI, myocardial infarction; CABG, coronary artery bypass grafting; COPD, chronic obstructive pulmonary disease; ACE, acetycholinesterase inhibitor; ASA, aspirin; NSAIDS, non-steroidal anti-inflammatory drugs.