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. 2003 Nov 7;6(1):R56–R64. doi: 10.1186/ar1022

Table 1.

Summary of effects of p38 MAPK inhibition on proteoglycan synthesis

Proteoglycan synthesis

Basal + TGF-β + IGF-1/FCS
SB No change - No change
IL-1 - - - - - -
IL-1 + SB* + No change No change

*Relative to IL-1 alone. FCS, fetal calf serum; IGF-1, insulin-like growth factor 1; SB, SB 203580; TGF-β, transforming growth factor beta.