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. 2003 Nov 7;6(1):R73–R77. doi: 10.1186/ar1026

Table 3.

Response, according to ACR criteria, of subjects in a trial of interferon-β-1a in patients with rheumatoid arthritis

Efficacy end point Response to placebo (n = 6) No. (%) Response to interferon (n = 16) No. (%) P valuea
ITT responder-at-end-point analysis
 ACR 20, week 12 1 (17) 3 (19) 0.71
 ACR 20, week 24 1 (17) 3 (19) 0.71
 ACR 50, week 24 0 (0) 2 (12.5) 0.51
 ACR70, week 24 0 0 0
ITT last-observation-carried-forward analysis
 ACR 20, week 24 2 (33) 7 (44) 0.52

aFisher's exact test; ACR 20 (50, 70), 20% (50%, 70%) improvement relative to baseline, according to ACR criteria.