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. 2014 Apr 2;53(14):2221–2231. doi: 10.1021/bi4017022

Table 1. Thermodynamic Parameters for 3WJs Formationa.

  1/Tm vs log (Ct)
3WJs ΔG°37 (kcal/mol) ΔH° (kcal/mol) ΔS°37(e.u.) Tmb (°C)
2′-F RNA –36 ± 0.45 –200 ± 5.7 –520 ± 17 72.1
RNA –28 ± 0.58 –170 ± 13 –440 ± 39 60.4
DNA –15 ± 0.71 –220 ± 25 –650 ± 83 35.2
a

Parameters derived from 15% native TGGE.

b

Tm values for 3WJ strand concentrations of 10–6 M.